If there is a particle, such as an electron, moving through space, I can characterize its motion by telling you where it is (its position) and its velocity (more precisely, its momentum).
This uncertainty leads to many strange things. For example, in a Quantum Mechanical world, I cannot then predict where a particle will be with 100 % certainty. I can only speak in terms of probabilities. For example, I can say that an atom will be at some location with a 99 % probability, but there will be a 1 % probability it will be somewhere else (in fact, there will be a small but finite probabilty that it will be found across the Universe). This is strange.
We do not know if this indeterminism is actually the way the Universe works because the theory of Quantum Mechanics is probably incomplete. That is, we do not know if the Universe actually behaves in this probabilistic manner (there are many possible paths a particle can follow and the observed path is chosen probabilistically) or if the Universe is deterministic in the sense that I can predict the path a particle will follow with 100 % certainty.
A consequence of the Qunatum Mechanical nature of the world, is that particles can appear in places where they have no right to be (from an ordinary, common sense [classical] point of view)!
This notion has interesting consequences for nuclear fusion in stars.