About

We study how the brain plans and controls complex, goal-directed skilled actions that resemble everyday behavior, and how these processes are disrupted by aging and disease. Our work integrates behavioral assays and controlled perturbations with biomechanics and advanced neuroimaging. Our long-term goal is to restore the grace, efficiency, and independence of skilled hand use for those who have lost it.

Core Research Areas

Flexibility vs. stereotypy in action planning and control
A central theme of our research is how the brain balances flexible, context-specific control with more stereotyped, default strategies. We study how factors such as sensory uncertainty and task repetition bias the system toward one mode or the other, and how this balance shifts with aging, leading to persistent errors and reduced adaptability in everyday behavior.

Sensorimotor interactions in action planning and control
Everyday actions depend on integrating multiple sensory signals, including vision and proprioception. We investigate how the brain weights these signals based on their reliability and how changes in sensory reliability influence both behavior and underlying neural representations across different components of an action.

Aging, disease, and loss of skilled function
We extend our work to understand how sensorimotor control is disrupted in aging and clinical populations. By understanding how changes in the motor system cause errors, we aim to define targets for interventions that preserve or restore functional independence.

Papers

Sager et al. 2025. Repetition hampers flexible object manipulation under visual uncertainty. European Journal of Neuroscience

Kreter et al. 2025. Sensory modality of initiation cues modulates action goal-relevant neural representations. Imaging Neuroscience.

Harris Caceres et al. 2024. Neural encoding of direction and distance across reference frames in visually guided reaching. eNeuro.

Sager et al. 2024. Repeated context-specific actions disrupt feedforward adjustments in motor commands in younger and older adults. Journal of Neurophysiology.

Marneweck et al. 2023. Reorganization of sensorimotor representations of the intact limb after upper but not lower limb traumatic amputation. NeuroImage: Clinical.

Bland, Davare, Marneweck, 2023. Visual information following object grasp supports digit position variability and swift anticipatory force control. Journal of Neurophysiology.

Mitchell, Marneweck* et al. 2021. Motor adaptation via distributional learning. Journal of Neural Engineering. *Joint co-first author.

Marneweck, Grafton, 2020. Overt and covert object features mediate timing of patterned brain activity during motor planning. Cerebral Cortex Communications.

Marneweck, Grafton, 2020. Neural substrates of anticipatory motor adaptation for object lifting. Nature Scientific Reports.

Marneweck, Grafton, 2020. Representational neural mapping of dexterous grasping before lifting in humans. Journal of Neuroscience.

Marneweck et al. 2018. Neural representations of sensorimotor memory- and digit position-based load force adjustments before the onset of dexterous object manipulation. Journal of Neuroscience.

Marneweck et al. 2018. The relationship between hand function and overlapping motor representations of the hands in the contralesional hemisphere in unilateral spastic cerebral palsy. Neurorehabilitation and Neural Repair.

Marneweck Flamand, 2016. Elucidating the neural circuitry underlying planning of internally-guided voluntary action. Journal of Neurophysiology.

Marneweck et al. 2016. Digit position and forces covary during anticipatory control of whole-hand manipulation. Frontiers in Human Neurosciences.

Lee-Miller et al. 2016. Visual cues of object properties differentially affect anticipatory planning of digit forces and placement. PLoS One.

Marneweck et al. 2015. Generalization of dexterous object manipulation is specific to the frame of reference in which it was learned. PLoS One

Marneweck, Vallence, 2015. The neural bases of different levels of action understanding. Journal of Neurophysiology.

Marneweck, Hammond, 2014. Voluntary control of facial musculature in Parkinson’s disease. Journal of the Neurological Sciences.

Marneweck, Hammond, 2014. Discriminating facial expressions of emotion and its link with perceiving visual form in Parkinson’s disease. Journal of the Neurological Sciences.

Marneweck et al. 2014. Discrimination and recognition of facial expressions of emotion and their links with voluntary control of facial musculature in Parkinson’s disease. Neuropsychology.

Marneweck et al. 2013. Psychophysical measures of sensitivity to facial expression of emotion. Frontiers in Psychology.

Marneweck et al. 2011. Short-interval intracortical inhibition and manual dexterity in healthy aging. Neuroscience Research.

People

Our lab is committed to rigorous, supportive, and increasingly independent scientific training. We aim to help trainees become thoughtful, technically strong, and creative researchers who can contribute meaningfully to the science of skilled action and sensorimotor control.

Michelle Marneweck, Principal Investigator


Michelle leads an independent research program in sensorimotor neuroscience focused on how the brain plans and controls complex, goal-directed skilled actions, and how these processes are disrupted by aging and disease. Her lab combines behavioral assays and controlled perturbations with biomechanics and advanced neuroimaging to identify the neural mechanisms that support dexterous, flexible action.

Her work centers on several linked questions: how the brain represents and plans skilled object manipulation; how sensory reliability shapes action planning; and why aging and other sensorimotor disruptions can bias behavior toward more stereotyped, less flexible control strategies. This work aims to identify mechanisms that support skilled hand use in everyday life and inform approaches to preserve or restore functional independence.

Originally from South Africa, Michelle completed her PhD at the University of Western Australia under Dr. Geoff Hammond, followed by postdoctoral training at Columbia University with Dr. Andrew Gordon and an NHMRC Early Career Fellowship with Drs. Scott Grafton and Gary Egan at the University of California, Santa Barbara and Monash University. She established her lab in the Department of Human Physiology at the University of Oregon in 2020.

Michelle also likes: surfing, skiing, hiking, mosaic hops, and Neopolitan style margarita pizzas.

Catherine Sager, PhD Candidate


Catherine is a PhD candidate in Human Physiology. Her research examines how aging and changing task demands influence flexible motor planning, with current work focused on when we plan multi-object actions and how those action plans are neurally encoded. She previously earned a B.S. in Neuroscience from the University of Iowa and later worked in brain sciences and clinical research while completing a master's degree in Psychology. Outside of research, she enjoys exploring the world, yapping, playing piano, and spending time with her husband and dog.

Philip Kurtz, PhD student


Philip is a PhD student in the Department of Human Physiology. He earned his M.Sc. in Clinical Exercise Science from the University of Potsdam, where he studied changes in neuromotor control related to Achilles tendinopathy. His current work focuses on proprioception, visually guided movement, and the neural control of sensorimotor behavior. In his spare time, Philip enjoys playing soccer, trekking, and cooking.

Ashley Jones, Research Assistant


Ashley is a fourth-year undergraduate at the University of Oregon majoring in Human Physiology with minors in Biology, Chemistry, and Global Health. She is interested in how motor learning and control are shaped by neurological and biomechanical factors, particularly in the context of neurodegenerative disease and rehabilitation. After graduating, Ashley plans to attend medical school. In her free time, she enjoys hiking, skiing, traveling, and spending time with friends.

Max Vester, Research Assistant


Max is a fourth-year undergraduate double majoring in Neuroscience and Human Physiology with a minor in Bioengineering. His interests span cellular and behavioral aspects of neuromotor control, and he is broadly interested in how the nervous system supports movement and function. While still deciding between medicine and research, he hopes to pursue a future related to neurology. Outside the lab, he enjoys running, reading, and being an absolute menace on the tennis court.

Daniel Johnson, Research Assistant


Daniel is a fourth-year undergraduate at the University of Oregon majoring in Data Science with a domain emphasis in Physics. He is interested in applying statistical analysis, machine learning, and programming to questions about motor control, brain function, and human health. He hopes to build computational tools that support research and discovery in biological and medical science. Outside of academics, he enjoys cooking, playing piano, playing and watching sports, and spending time outdoors.

[Your name here]


We are currently recruiting graduate students and research assistants interested in behavioral and systems neuroscience, with an emphasis on motor control and skilled action. We welcome applicants interested in designing, programming, and conducting biomechanics, neuroimaging, and brain stimulation experiments in healthy and clinical populations.

The lab is committed to fostering a diverse, equitable, and inclusive research and training environment, and to maintaining a fun, rigorous, and supportive research environment.

If you are interested in joining the lab as a PhD student, postdoc, or research assistant, please email Michelle.

Contact

Join our lab and live in a place where beauty is around every corner! We have exciting positions starting Fall 2027. We will be accepting graduate students through the Department of Human Physiology Research PhD Program.

Please e-mail Michelle if interested. I support all students regardless of immigration status or country of origin.

Diversity, Equity, & Inclusion

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Our commitment to diversity, equity, and inclusion is embedded in how we conduct research, train scientists, and build our lab community. We aim to create an environment in which individuals from diverse backgrounds feel a strong sense of belonging and are supported in developing as independent, rigorous scientists.

We operationalize these values through intentional mentorship, transparent expectations, and inclusive research and recruitment practices. This includes actively seeking diverse trainee pools, fostering respectful and open scientific dialogue, and co-developing lab norms that support collaboration, accountability, and equitable participation.

Our group norms:
  • We acknowledge that disagreement can be beneficial. We value disagreeing in a respectful manner and without interrupting. We disagree with ideas, but do not attack the person presenting the idea. Be open to constructive feedback. Make others feel comfortable to participate when disagreeing on topics.
  • We will be open to others’ ideas by actively listening and take all ideas seriously and openly. We will provide feedback in a respectful manner by not attacking people or being dismissive of their contributions. We acknowledge that disagreement can be beneficial and value disagreeing in a respectful manner.
  • Nurture an environment where everyone is supported, celebrated, and able to do their best work. Lift each other up and celebrate individual and community achievements. Remember how lucky we are to be doing what we love in and through the context of our jobs.
  • Aim for transparency in processes whenever possible. Communicate process steps or process change efforts with an understanding that not everyone knows existing or historical contexts. Provide clear expectations and feedback. Be transparent in taking accountability for one's actions without placing blame on someone else.
  • Encourage a mindset of ongoing learning and development. Support team members in acquiring new skills, attending relevant workshops, and staying informed about emerging trends in the field. We encourage the development of mentoring relationships.
  • Ask for help when needed and provide possible solutions and/or help to others when you can.

Lab Outings and Pets

Lab Outings

Opening lab stockings

Opening lab stockings (ft Max and Michelle in their mii forms).

Tailgating at Autzen Stadium

Tailgating at Autzen Stadium.

Holiday celebration

Holiday celebration.

Paint and pass craft day

Paint and pass craft day.

Trivia at Gratitude Brewing

Trivia at Gratitude Brewing.

Celebrating end of term

Celebrating end of term.

Baseball game for the Eugene Emeralds

Baseball game for the Eugene Emeralds.

Catherine and Nick with colleague in Dubrovnik for Neural Control of Movement conference

Catherine and Nick with colleague in Dubrovnik for Neural Control of Movement conference.

Lab Pets

Catherine's cats

Catherine's cats.

Catherine's dog Malcolm

Catherine's dog Malcolm.

Malcolm on a hike at Spencer Butte

Malcolm on a hike at Spencer Butte.