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Date: Thu, 05 Nov 2009 13:40:29 -0500
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Grant Clinic
Reader Question: We are in the process of applying for a grant to extend pr=
omising preliminary results. But should we also include mention of some con=
tradictory data we found? This would demonstrate we did extra hours of work=
, but will it undercut our chances for funding?
Expert Comments: As to the "extra" hours of work you put in, nobody cares. =
Only results count.=20
The first purpose in presenting preliminary data is to demonstrate feasibil=
ity and that you have the necessary expertise to carry out the procedures y=
ou propose in the Research Methods section. I believe it doesn't matter if =
you have some contradictory results, or even that the data you are describi=
ng were collected for other purposes in a different study. The focus in thi=
s section is not on the results per se, but on the fact that you were succe=
ssfully able to collect and analyze the data.=20
But pilot data showing positive results, are potent evidence. They indicate=
that you are on the right track. The reviewers will weight this heavily. T=
here are subtleties to reporting these, however. The possible variations in=
volve (1) primacy of the outcomes; (2) positive/null/negative results; and =
(3) statistical power of your pilot study to detect effects. Here are the p=
ossibilities:=20
View the remainder of the expert comments (XXXXXXXwww.principalinvestigator=
s.org/newsDetail.php?Grant-Clinic-Contradictory-Data-4)
Comments by William Gerin, Ph.D., Professor of Biobehavioral Health, Pennsy=
lvania State University Author, Writing the NIH Grant Proposal: A Step-by-S=
tep Guide, SAGE Books (2006)
Agree? Disagree? Submit your comments (XXXXXXXwww.principalinvestigators.or=
g/newsDetail.php?Grant-Clinic-Contradictory-Data-4#comments)
=20
??Preview of Next Week's Question??
Reader Question: The regional sales manager of an equipment manufacturer fr=
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ers. Should academics like us accept such? Why or why not? Also would it ma=
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=20
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=0A <td><strong><font =0Aface=3D"sans-serif" size=3D=
"5">Grant Clinic</font></strong>
=0A =0A<p><font =0Asize=3D"2"><b>Reader Question:</b=
> =0A<em>We are in the process of applying for a grant to extend promising =
preliminary results. But should we also include mention of some contradicto=
ry data we found? This would demonstrate we did extra hours of work, but wi=
ll it undercut our chances for funding?</em></font></p>
=0A =0A<p><font =0Asize=3D"2"><b>Expert Comments:</b=
> =0AAs to the "extra" hours of work you put in, nobody cares. On=
ly results count. </font></p>
=0A =0A<p><font =0Asize=3D"2">The first purpose in p=
resenting preliminary data is to demonstrate feasibility and that you have =
the necessary expertise to carry out the procedures you propose in the Rese=
arch Methods section. I believe it doesn't matter if you have some contradi=
ctory results, or even that the data you are describing were collected for =
other purposes in a different study. The focus in this section is not on th=
e results per se, but on the fact that you were successfully able to collec=
t and analyze the data. </font></p>
=0A =0A<p><font =0Asize=3D"2">But pilot data showing=
positive results, are potent evidence. They indicate that you are on the r=
ight track. The reviewers will weight this heavily. There are subtleties to=
reporting these, however. The possible variations involve (1) primacy of t=
he outcomes; (2) positive/null/negative results; and (3) statistical power =
of your pilot study to detect effects. Here are the possibilities: </font><=
/p>
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mainder of the expert comments</a></font></p>
=0A =0A<p><font =0Asize=3D"2"><em>Comments by=0A <b>=
William Gerin,</b> =0APh.D., Professor of Biobehavioral Health, Pennsylvani=
a State University Author,=0A <u>Writing the NIH Grant Proposal: A Step-by-=
Step Guide</u>, =0ASAGE Books (2006)</em></font></p>
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and my grad students out to a nice dinner during the upcoming national meet=
ing of our research specialty. We obviously are already good customers. Sho=
uld academics like us accept such? Why or why not? Also would it matter if =
we were merely "prospective" customers instead of proven ones?</e=
m></font></p>
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