C. elegans is a powerful model system for studying genetics, development, and neurobiology. The Phillips lab has helped pioneer the use of this species for evolutionary studies, particularly for experimental evolution. We are expanding this work into the molecular population genomic analysis of the closely related species, C. remanei, which has much more genetic variation.
Timmermeyer, N., S.A. Banse, J.H. North, M. Sottile, S.R. Lockery, and P.C. Phillips. An open source worm sorter: robust sorting of Caenorhabditis nematodes using PDMS microfluidic chips.
Phillips, P.C. Modeling evolutionary theories. In S. Scheiner and D. Mindell (eds.), Theory in Evolutionary Biology.Lucanic, M., W.T. Plummer, E. Chen, J. Harke, D. Bhaumik, B. Onken, A.L. Coleman-Hulbert, K.J. Dumas, S. Guo, E. Johnson, A.C. Foulger, C. Chang, A.B. Crist, M.P. Presley, J. Xue, C.A. Sedore, M. Chamoli, G. Harinath, M.K. Chen, S. Angeli, M.A. Royal, J.H. Willis, D. Edgar, S. Patel, E.A. Chao, S. Kamat, J. Hope, C. Ibznez-Ventoso, J.L. Kish, M. Guo, G.J. Lithgow, M. Driscoll, and P.C. Phillips. 2016. Aging interventions across Caenorhabditis species identify unexpected challenges for reproducibility.